Anti-leishmanial

Diacetylpiptocarphol
Catalog No: CFN97859

Diacetylpiptocarphol shows antileishmanial activity against three stages of Leishmania infantum.

5-Galloylquinic acid
Catalog No: CFN92078

5-Galloylquinic acid as an index for the baking intensity of oolong teas. It has antioxidant activity.

Trametenolic acid
Catalog No: CFN92366

Trametenolic acid is a cytotoxic agent.It exhibits a mode of mixed inhibition with a K I of 0.9 μM, K IS of 0.5 μM, and an IC50 of 7.25 μM.Trametenolic acid and Betulin as a new candidate of potent tyrosinase inhibitors, can decrease tyrosinase activity and melanin content.

Skimmianin
Catalog No: CFN92555

Skimmianine is a new inhibitor against the Leishmania APRT enzyme, it is also a strong acetylcholinesterase (AChE) inhibitor. Skimmianine has anti-inflammatory, immunomodulatory, and leishmanicidal properties, it has a selective inhibitory effect on the 5-hydroxytryptamine-induced vasopressor responses of rats.

Amarogentin
Catalog No: CFN90519

Amarogentin incorporated in liposomes or niosomes may have clinical application in the treatment of leishmaniasis. It plays cemopreventive/therapeutic role during liver carcinogenesis through modulation of cell cycle and apoptosis. Amarogentin may offer therapeutic potential for preventing or treating thromboembolic disorders, it prevents platelet activation through the inhibition of PLC γ2-PKC cascade and MAPK pathway.